KidiPeg®


(Pegylated Filgrastim)

This Chapter Has a Good Ending…


Overview

KidiPeg® contains Pegfilgrastim. Pegfilgrastim is a man-made form of granulocyte colony-stimulating factor (G-CSF). G-CSF is a substance produced by the body. It stimulates the growth of neutrophils, a type of white blood cell important in the body’s fight against infection.

Dosage Forms and Strengths

3 mg per 0.3 mL in single use prefilled syringe.

Indication and Usage

  • It is used to lower the chance of getting an infection in cancer patients who have had very bad bone marrow problems caused by chemotherapy.
  • It is used to lower the chance of getting an infection in patients who receive radiotherapy.

How to Use?

  • KidiPeg® should be administered in a hospital or a clinic under the supervision of a doctor.
  • KidiPeg® is provided in a prefilled syringe. It is given as a shot into the fatty part of the skin.
  • To gain the most benefit, do not miss doses.
  • Do not shake the solution.
  • Before giving the shot, let it come to room temperature. Do not heat this drug.
  • Wash hands before and after use.
  • Do not use if the solution is cloudy, leaking, or has particles.
  • Do not use if solution changes color.
  • Do not use if this drug has been frozen more than once.
  • Do not give into the red or irritated skin.
  • Move the site where you give the shot with each shot.
  • Throw syringe away after use. Do not use more than one time.
  • Store in a refrigerator (2-8°C). Do not freeze.
  • You can store pre-filled syringe at room temperature for 2 days.
  • KidiPeg® should be stored in its carton to protect from light until use.
  • Keep all drugs out of the reach of children and pets.
  • Throw out unused drugs.

What should I know BEFORE treatment?

Tell your doctor BEFORE the patient takes this drug:

  • If the patient has an allergy to pegfilgrastim, filgrastim, or any other part of this drug.
  • If the patient is allergic to any drugs like this one, any other drugs, foods, or other substances.  
  • Tell the doctor about the allergy and what signs the patient had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • Tell the doctor if the patient have sickle cell disease.
  • If the patient is allergic to acrylics, talk with the doctor.
  • This drug may interact with other drugs or health problems. Tell the doctor and pharmacist about all of the patient’s drugs (prescription or OTC, natural products, vitamins) and health problems. It must be checked to make sure that it is safe for the patient to take this drug with all of the patient’s drugs and health problems. Do not start, stop, or change the dose of any drug without checking with the doctor.

What should I know DURING treatment?

  • Tell dentists, surgeons, and other doctors that the patient uses this drug.
  • Sometimes pain and redness occur at the injection site. Tell the doctor if the patient has swelling, bumps, and bruises after injection that have not been removed.
  • If the patient has a latex allergy, talk with the doctor.
  • This drug should not be injected within 14 days before and also until approximately 24 hours after receiving chemotherapy.
  • If the patient has a sickle cell disorder, make sure that the doctor knows about it before starting to use this drug. If the patient has a sickle cell crisis after getting KidiPeg®, tell the doctor right away.
  • KidiPeg® can cause serious allergic reactions. These reactions can cause the rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. If the patient has an allergic reaction during the injection of KidiPeg®, stop the injection. Call the doctor right away.
  • If the patient has pain in upper left part of abdomen or pain in shoulders after KidiPeg® administration tell the doctor.
  • Monitor the patient’s white blood cells on a regular basis.
  • Tell the doctor if the patient has a problem in urination, blood in the urine or sudden weight gain.
  • Tell the doctor if the patient has a fever and painful skin lesions that mostly occurs on the arms, neck, head, and trunk.
  • Tell the doctor if the patient missed one dose.
  • Keep the part of the body which is planned to be injected dry for 3 hours before drug injection.
  • Do not apply pressure on the injection site.

Adverse Reactions / Side Effects

The most common side effect the patient may experience is aching in the bones and muscles. If this happens, it can usually be relieved with a non-aspirin pain reliever, such as acetaminophen.

What should I do if I miss a dose?

  • Call your doctor to find out what to do.

Contact Patient Support

If you notice any effects that are not listed above, discuss them with your doctor or click here to see Orchid Pharmed Patient Support Center contact details.

How Supplied / Storage and Handling

  • KidiPeg® should be stored in the refrigerator at 2 to 8°C (36° to 46°F), but not in the freezer.
  • KidiPeg® should be protected from light, so you should keep it in its carton until the patient is ready to use it.
  • Avoid shaking KidiPeg®.
  • If KidiPeg® is accidentally frozen, allow it to thaw in the refrigerator before injecting. However, if it is frozen a second time, do not use it.
  • KidiPeg® Pre-filled syringe can be left out at room temperature for up to 48 hours. 
  • Do not leave KidiPeg® in direct sunlight.