PegaGen®


(Pegylated Filgrastim)

Bone Pain Flies Away ...


PegaGen® (Pegfilgrastim)

Prefilled syringe: 6 mg / 0.6 ml in single use

What is PegaGen?

  • PegaGen contains Pegfilgrastim. Pegfilgrastim is a man-made form of granulocyte colony-stimulating factor (G-CSF). G-CSF is a substance produced by the body. It stimulates the growth of neutrophils, a type of white blood cell important in the body’s fight against infection.

 

What is PegaGen used for?

  •  It is used to lower the chance of getting an infection in cancer patients who have had very bad bone marrow problems caused by chemotherapy.

What should I know BEFORE taking PegaGen?

       Tell your doctor BEFORE you take this drug?

  •  If you have an allergy to pegfilgrastim, filgrastim, or any other part of this drug.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you are allergic to acrylics, talk with your doctor.
  • This drug may interact with other drugs or health problems.
  • Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take this drug with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this drug while you are pregnant.
  •  Tell your doctor if you are breastfeeding.

How should I take this drug?

  • PegaGen is provided in a prefilled syringe. It is given as a shot into the fatty part of the skin.
  • To gain the most benefit, do not miss doses.
  •  Do not shake the solution.
  •  Before giving the shot, let it come to room temperature. Do not heat this drug.
  •  Wash your hands before and after use.
  •  Do not use if the solution is cloudy, leaking, or has particles.
  •  Do not use if solution changes color.
  •  Do not use if this drug has been frozen more than once.
  •  Do not give into red or irritated skin.
  •  Move the site where you give the shot with each shot.
  •  Throw syringe away after use. Do not use more than one time.
  •  Store in a refrigerator. Do not freeze.
  •  You may store at room temperature for 2 days.
  •  PegaGen should be stored in its carton to protect from light until use.
  •  Keep all drugs out of the reach of children and pets.
  •  Throw out unused drugs.

What should I know while taking this drug?

  •  Tell dentists, surgeons, and other doctors that you use this drug.
  •  If you have a latex allergy, talk with your doctor.
  • This drug should not be injected within 14 days before and also until approximately 24 hours after receiving chemotherapy.
  • If you have a sickle cell disorder, make sure that your doctor knows about it before you start using this drug. If you have a sickle cell crisis after getting PegaGen, tell your doctor right away.
  • PegaGen can cause serious allergic reactions.  These reactions can cause rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. If you have an allergic reaction during the injection of PegaGen, stop the injection. Call your doctor right away.
  • The most common side effect you may experience is aching in the bones and muscles. If this happens, it can usually be relieved with a non-aspirin pain reliever, such as acetaminophen.
  •  

Pregnancy and Lactation

·         C/ Use with caution

How should PegaGen be stored?

  • PegaGen should be stored in the refrigerator at 2° to 8°C (36° to 46°F), but not in the freezer.
  •  PegaGen should be protected from light, so you should keep it in its carton until you are ready to use it.
  • Avoid shaking PegaGen.
  • If PegaGen is accidentally frozen, allow it to thaw in the refrigerator before injecting. However, if it is frozen a second time, do not use.
  • PegaGen can be left out at room temperature for up to 48 hours. Do not leave PegaGen in direct sunlight

 

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